Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27441058 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1TDP1MEN1LMNA | |
| SCHEMBL5221403 | 0.85 | L3MBTL1 (0.64) | KDM4EALDH1A1TDP1MEN1LMNA | |
| SCHEMBL27441053 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1TDP1MEN1LMNA | |
| SCHEMBL27441052 | 0.81 | RET (0.46) | KDM4EALDH1A1TDP1MEN1LMNA | |
| SCHEMBL29998882 | 0.81 | RET (0.46) | KDM4EALDH1A1TDP1MEN1LMNA | |
| SCHEMBL23657160 | 0.79 | CTSK (0.47) | KDM4EALDH1A1HSD17B10HPGDCTSK | |
| SCHEMBL29771089 | 0.79 | CTSK (0.47) | KDM4EALDH1A1HSD17B10HPGDCTSK | |
| SCHEMBL29658820 | 0.77 | JAK3 (0.47) | CTSKCKS1BSKP1SKP2OPRM1 | |
| SCHEMBL19734920 | 0.77 | CTSK (0.45) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL19734602 | 0.77 | JAK3 (0.47) | CTSKCKS1BSKP1SKP2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199662-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | 四川汇宇制药股份有限公司 | 2022-09-29 | — | — | WO | disclosed |