Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27441058 | 0.85 | KDM4E (0.48) | L3MBTL1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL29998614 | 0.85 | KDM4E (0.48) | L3MBTL1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL4097876 | 0.84 | P2RY12 (0.63) | KDM4EALDH1A1KMT2AOPRK1P2RY12 | |
| Hydrochloric Acid SCHEMBL5225308 | 0.81 | L3MBTL1 (0.74) | L3MBTL1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3281938 | 0.79 | L3MBTL1 (0.58) | L3MBTL1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL27441053 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL19734920 | 0.76 | CTSK (0.45) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL29998882 | 0.76 | RET (0.46) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL27441052 | 0.76 | RET (0.46) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL29658635 | 0.76 | JAK3 (0.49) | KDM4EALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |