Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30053701 | 0.78 | ALDH1A1 (0.40) | MAPTPOLBNPC1KDM4EKMT2A | |
| SCHEMBL28419039 | 0.78 | ALDH1A1 (0.40) | MAPTPOLBNPC1KDM4EKMT2A | |
| SCHEMBL14534667 | 0.78 | MAPT (0.46) | MAPTPOLBGLARAB9ANPC1 | |
| SCHEMBL29560210 | 0.76 | AGBL2 (0.33) | — | |
| SCHEMBL22866555 | 0.76 | AGBL2 (0.33) | — | |
| SCHEMBL31310145 | 0.75 | GAA (0.43) | MAPTPOLBGLAKMT2AALDH1A1 | |
| SCHEMBL13728103 | 0.75 | MAPT (0.46) | MAPTPOLBGLARAB9ANPC1 | |
| SCHEMBL3355225 | 0.74 | KMT2A (0.41) | MAPTPOLBGLARAB9ANPC1 | |
| SCHEMBL17512586 | 0.73 | MAPT (0.55) | MAPTPOLBGLARAB9ANPC1 | |
| SCHEMBL29999860 | 0.73 | NPC1 (0.46) | MAPTPOLBGLARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264113-A | GSPT1 degradation agent and application thereof | 江苏运动健康研究院 | 2025-01-07 | — | — | CN | disclosed |