Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | USP1 | O94782 | 2/20 | 0.47 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26697704 | 0.82 | VNN1 (0.46) | MAPTMAP2K4EGFRPOLBNR2F2 | |
| SCHEMBL29936014 | 0.82 | VNN1 (0.46) | MAPTMAP2K4EGFRPOLBNR2F2 | |
| SCHEMBL31240859 | 0.76 | NPC1 (0.48) | PTK2USP1WDR48MAPTTP53 | |
| SCHEMBL27088827 | 0.76 | MAPT (0.45) | PTK2USP1WDR48MAPTTP53 | |
| SCHEMBL312225 | 0.75 | NPC1 (0.58) | PTK2USP1WDR48MAPTTP53 | |
| SCHEMBL15538052 | 0.75 | USP1 (0.53) | PTK2USP1WDR48MAPTTP53 | |
| SCHEMBL30873414 | 0.75 | LMNA (0.40) | MAPT | |
| SCHEMBL7170316 | 0.73 | APP (0.50) | MAPTMAP2K4EGFRPOLBNR2F2 | |
| SCHEMBL25804769 | 0.72 | PTK2 (0.49) | PTK2USP1WDR48MAPTTP53 | |
| SCHEMBL17011498 | 0.71 | MAPT (0.47) | MAPTMAP2K4EGFRPOLBNR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049274-A2 | TETRACYCLIC DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| EP-4320132-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | Genentech, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216762-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | GENENTECH, INC. (US) | 2022-10-13 | — | — | WO | disclosed |