Zanvipixant

Zanvipixant

SCHEMBL30001656

C[C@H]1Cc2c(nnn2-c2ncc(F)cn2)CN1C(=O)c1ccnc(C(F)(F)F)c1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 20/20 1.00
CYP2C19 P33261 5/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zanvipixant SCHEMBL31347780 1.00 P2RX7 (1.00) P2RX7CYP2C19
Zanvipixant SCHEMBL16035842 1.00 P2RX7 (1.00) P2RX7CYP2C19
Zanvipixant SCHEMBL16035844 1.00 P2RX7 (1.00) P2RX7CYP2C19
SCHEMBL16127677 0.94 P2RX7 (1.00) P2RX7CYP2C19
SCHEMBL17509159 0.94 P2RX7 (1.00) P2RX7CYP2C19
SCHEMBL31567839 0.93 P2RX7 (1.00) P2RX7CYP2C19
SCHEMBL16089637 0.92 P2RX7 (1.00) P2RX7CYP2C19
SCHEMBL29689577 0.92 P2RX7 (1.00) P2RX7CYP2C19
SCHEMBL16036929 0.92 P2RX7 (1.00) P2RX7CYP2C19
SCHEMBL16036926 0.92 P2RX7 (1.00) P2RX7CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367144-A1 TREATMENT OF HYPERINFLAMMATORY SYNDROME REMICINE IP B V (NL) 2025-12-04 US disclosed
US-12419848-B2 Treatment of hyperinflammatory syndrome Remicine IP B.V. (NL) 2025-09-23 US disclosed
EP-4582147-A2 TREATMENT OF HYPERINFLAMMATORY SYNDROME Remicine IP B.V. (NL) 2025-07-09 EP disclosed
US-20250195855-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT GLAS USA LLC 2025-06-19 US disclosed
EP-4125843-B1 TREATMENT OF HYPERINFLAMMATORY SYNDROME REMICINE IP B V (NL) 2025-05-21 EP disclosed
EP-4493258-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT Biora Therapeutics, Inc. (US) 2025-01-22 EP disclosed
CN-119173296-A Ingestible devices for delivering therapeutic agents to the gastrointestinal tract 比奥拉治疗股份有限公司 2024-12-20 CN disclosed
EP-3870261-B1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT BIORA THERAPEUTICS INC (US) 2024-01-31 EP disclosed
EP-4309722-A2 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT Biora Therapeutics, Inc. (US) 2024-01-24 EP disclosed
WO-2023178354-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT BIORA THERAPEUTICS, INC. (US) 2023-09-21 WO disclosed
US-11707610-B2 Ingestible device for delivery of therapeutic agent to the gastrointestinal tract BIORA THERAPEUTICS, INC. (US) 2023-07-25 US disclosed
US-20230149315-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT GLAS USA LLC 2023-05-18 US disclosed
US-20230128348-A1 TREATMENT OF HYPERINFLAMMATORY SYNDROME Remicine IP B.V. (NL) 2023-04-27 US disclosed
EP-4125843-A1 TREATMENT OF HYPERINFLAMMATORY SYNDROME Nomoreitis B.V. (BE) 2023-02-08 EP disclosed
CN-115666704-A Ingestible device for delivery of therapeutic agents to the gastrointestinal tract 比奥拉治疗股份有限公司 2023-01-31 CN disclosed
CN-115605194-A Treatment of excessive inflammatory syndrome 诺莫雷蒂斯私人有限公司(BE) 2023-01-13 CN disclosed
US-20220326258-A1 BIOMARKERS FOR AMYOTROPHIC LATERAL SCLEROSIS (ALS) AND MOTOR NEURON DISEASES NORTHWESTERN UNIVERSITY 2022-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11707610-B2 Ingestible device for delivery of therapeutic agent to the gastrointestinal tract MUC1, SLC10A2, FABP2 P2RX7 1356/4885CYP2C19 2728/4885
US-20230149315-A1 INGESTIBLE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT TO THE GASTROINTESTINAL TRACT MUC1, SLC10A2, FABP2 P2RX7 1356/4885CYP2C19 2728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.