Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13374829 | 0.92 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL22163627 | 0.91 | HDAC1 (0.62) | ALDH1A1MEN1KMT2AHDAC1PKM | |
| SCHEMBL30002126 | 0.91 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AHDAC1PKM | |
| SCHEMBL30001961 | 0.89 | HDAC1 (0.53) | ALDH1A1MEN1KMT2AHDAC1PKM | |
| SCHEMBL22163586 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL30002074 | 0.85 | MAOB (0.54) | ALDH1A1MEN1KMT2AHDAC1PKM | |
| SCHEMBL10233953 | 0.84 | NPC1 (0.53) | ALDH1A1MEN1KMT2AHDAC1SMN1; SMN2 | |
| SCHEMBL30002029 | 0.83 | MEN1 (0.54) | MEN1KMT2AHDAC1PKMSMN1; SMN2 | |
| SCHEMBL23419975 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL13374831 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117677382-A | Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling | 阿米蒂比奥有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117677382-A | Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling | 阿米蒂比奥有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110325509-B | Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same | 阿米蒂比奥有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116836083-A | Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same | 阿米蒂比奥有限公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2022255801-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | (주)앰틱스바이오 | 2022-12-08 | — | — | WO | disclosed |