SCHEMBL30002029

SCHEMBL30002029

CN1CCC[C@H]1C(=O)NCc1ccc(OCc2ccc(Cl)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
HDAC1 Q13547 6/20 0.53
HDAC2 Q92769 3/20 0.53
HDAC3 O15379 1/20 0.53
HRH3 Q9Y5N1 1/20 0.51
PKM P14618 1/20 0.51
HDAC6 Q9UBN7 1/20 0.49
MMP1 P03956 1/20 0.48
ADAM17 P78536 1/20 0.48
SLC6A5 Q9Y345 1/20 0.48
PTGER4 P35408 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111166 0.90 HDAC1 (0.61) HDAC1HDAC2HDAC3PKMHDAC6
SCHEMBL21696570 0.90 MEN1 (0.57) MEN1KMT2AHRH3PKM
SCHEMBL30002109 0.86 SLC6A5 (0.58) HDAC1HDAC2HDAC3HRH3SLC6A5
SCHEMBL30002020 0.83 ALDH1A1 (0.65) MEN1KMT2AHDAC1HDAC2PKM
SCHEMBL30001630 0.83 MAOB (0.60) HDAC1HDAC2HDAC3MMP1ADAM17
SCHEMBL30002303 0.80 SLC6A5 (0.53) KMT2ASLC6A5
SCHEMBL14287797 0.80 HRH3 (0.58) HRH3PTGER4SMN1; SMN2
SCHEMBL17136513 0.79 MMP8 (0.53) MEN1KMT2AHDAC1HDAC2HDAC3
SCHEMBL21696758 0.79 FKBP1A (0.58) MEN1KMT2APKMSMN1; SMN2
SCHEMBL21697246 0.79 FKBP1A (0.58) MEN1KMT2APKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION AMTIXBIO CO., LTD. (KR) 2025-06-26 US claimed
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
US-20250034085-A1 COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
EP-4349329-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION Amtixbio Co., Ltd. (KR) 2024-04-10 EP claimed
CN-117677382-A Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling 阿米蒂比奥有限公司 2024-03-08 CN claimed
CN-110325509-B Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2024-02-02 CN claimed
WO-2022255801-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION (주)앰틱스바이오 2022-12-08 WO claimed
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION AMTIXBIO CO., LTD. (KR) 2025-06-26 US disclosed
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES AMTIXBIO CO., LTD. (KR) 2025-01-30 US disclosed
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS AMTIXBIO CO., LTD. (KR) 2025-01-30 US disclosed
US-20250034085-A1 COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION AMTIXBIO CO., LTD. (KR) 2025-01-30 US disclosed
US-20250034082-A1 FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AMTIXBIO CO., LTD. (KR) 2025-01-30 US disclosed
EP-4349329-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION Amtixbio Co., Ltd. (KR) 2024-04-10 EP disclosed
CN-117677382-A Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling 阿米蒂比奥有限公司 2024-03-08 CN disclosed
CN-110325509-B Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2024-02-02 CN disclosed
CN-116836083-A Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2023-10-03 CN disclosed
WO-2022255801-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION (주)앰틱스바이오 2022-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES BCAT2, BCAT1, DAO MEN1 2172/4885KMT2A 1657/4885HDAC1 3967/4885
US-20250034082-A1 FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME PEPD, BCAT1, ANPEP MEN1 2657/4885KMT2A 3096/4885HDAC1 2889/4885
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS ERG28, BCAT2, AADAT MEN1 1063/4885KMT2A 3000/4885HDAC1 3661/4885
US-20250034085-A1 COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION PEPD, PREP, ANPEP MEN1 2795/4885KMT2A 3439/4885HDAC1 3497/4885
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION TSLP, IL2RA, TRPC7 MEN1 4612/4885KMT2A 3585/4885HDAC1 3995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.