Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002126 | 0.90 | ALDH1A1 (0.56) | SIRT2ALDH1A1HDAC1MEN1KMT2A | |
| SCHEMBL22163627 | 0.89 | HDAC1 (0.62) | SIRT2ALDH1A1HDAC1MEN1KMT2A | |
| SCHEMBL30001961 | 0.85 | HDAC1 (0.53) | SIRT2ALDH1A1HDAC1MEN1KMT2A | |
| SCHEMBL30002020 | 0.85 | ALDH1A1 (0.65) | SIRT2ALDH1A1HDAC1MEN1KMT2A | |
| SCHEMBL30001630 | 0.85 | MAOB (0.60) | MAOBMAOAALDH1A1HDAC1SCN9A | |
| SCHEMBL7989544 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL20510488 | 0.83 | ALDH1A1 (0.52) | SIRT2ALDH1A1MEN1KMT2AAPP | |
| SCHEMBL20510486 | 0.83 | ALDH1A1 (0.52) | SIRT2ALDH1A1MEN1KMT2AAPP | |
| SCHEMBL30001634 | 0.83 | GPR119 (0.52) | MAOBMAOAALDH1A1SCN9A | |
| SCHEMBL28629216 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117677382-A | Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling | 阿米蒂比奥有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117677382-A | Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling | 阿米蒂比奥有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110325509-B | Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same | 阿米蒂比奥有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116836083-A | Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same | 阿米蒂比奥有限公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2022255801-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | (주)앰틱스바이오 | 2022-12-08 | — | — | WO | disclosed |