Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ4 | P56696 | 3/20 | 0.45 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046953 | 1.00 | KCNQ4 (0.45) | KCNQ4KCNQ5CYP17A1P2RX3BRAF | |
| SCHEMBL29468015 | 0.89 | CYP17A1 (0.49) | KCNQ4KCNQ5CYP17A1P2RX3RXFP1 | |
| SCHEMBL22411865 | 0.87 | KCNQ4 (0.46) | KCNQ4KCNQ5CYP17A1P2RX3BRAF | |
| SCHEMBL31172075 | 0.86 | KCNQ4 (0.47) | KCNQ4KCNQ5CYP17A1P2RX3BRAF | |
| SCHEMBL22411949 | 0.86 | KCNQ4 (0.47) | KCNQ4KCNQ5CYP17A1P2RX3BRAF | |
| SCHEMBL28928511 | 0.85 | LOXL2 (0.44) | KCNQ4KCNQ5RAB9ALOXL2HTT | |
| SCHEMBL27915724 | 0.84 | AAK1 (0.46) | KCNQ4KCNQ5CYP17A1AAK1NR1H2 | |
| SCHEMBL7344988 | 0.84 | AAK1 (0.47) | KCNQ4KCNQ5CYP17A1AAK1NR1H2 | |
| SCHEMBL1726357 | 0.84 | LMNA (0.51) | KCNQ4KCNQ5CYP17A1RXFP1GAA | |
| SCHEMBL4304475 | 0.83 | RAB9A (0.53) | KCNQ4KCNQ5RXFP1RAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332687-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | SANOFI (FR) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332687-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | KCNQ4 3167/4885KCNQ5 2347/4885CYP17A1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.