Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189085 | 1.00 | NAAA (0.52) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL27189102 | 1.00 | NAAA (0.52) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL27189089 | 1.00 | NAAA (0.52) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL27189091 | 1.00 | NAAA (0.52) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL27189079 | 1.00 | NAAA (0.52) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL29205214 | 0.91 | ALDH1A1 (0.50) | SMN1; SMN2HDAC3HDAC1MAPTGAA | |
| SCHEMBL6930398 | 0.91 | NAAA (0.62) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL27189080 | 0.88 | HDAC1 (0.49) | NAAASMN1; SMN2HDAC3HDAC1HPGD | |
| SCHEMBL863113 | 0.88 | SMN1; SMN2 (0.52) | L3MBTL1SMN1; SMN2HDAC3HDAC1MAPT | |
| SCHEMBL10244608 | 0.85 | SMN1; SMN2 (0.58) | NAAAL3MBTL1SMN1; SMN2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255499-A1 | NOVEL AMP-ACTIVATED PROTEIN KINASE ACTIVATOR | 学校法人京都薬科大学 | 2022-12-08 | — | — | WO | disclosed |