SCHEMBL6930398

SCHEMBL6930398

CCCCCCNC(=O)c1ccsc1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 4/20 0.62
L3MBTL1 Q9Y468 1/20 0.60
HDAC1 Q13547 2/20 0.55
HDAC3 O15379 1/20 0.55
MLYCD O95822 1/20 0.55
CA2 P00918 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.51
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
KDM4E B2RXH2 1/20 0.48
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10244608 0.94 SMN1; SMN2 (0.58) NAAAL3MBTL1HDAC1HDAC3MLYCD
SCHEMBL27189085 0.91 NAAA (0.52) NAAAL3MBTL1HDAC1HDAC3MLYCD
SCHEMBL27189089 0.91 NAAA (0.52) NAAAL3MBTL1HDAC1HDAC3MLYCD
SCHEMBL27189091 0.91 NAAA (0.52) NAAAL3MBTL1HDAC1HDAC3MLYCD
SCHEMBL30002337 0.91 NAAA (0.52) NAAAL3MBTL1HDAC1HDAC3MLYCD
SCHEMBL27189102 0.91 NAAA (0.52) NAAAL3MBTL1HDAC1HDAC3MLYCD
SCHEMBL27189079 0.91 NAAA (0.52) NAAAL3MBTL1HDAC1HDAC3MLYCD
SCHEMBL3641810 0.87 HDAC1 (0.56) NAAAL3MBTL1HDAC1HDAC3CA2
SCHEMBL863113 0.82 SMN1; SMN2 (0.52) L3MBTL1HDAC1HDAC3SMN1; SMN2ALDH1A1
SCHEMBL845966 0.81 L3MBTL1 (0.86) NAAAL3MBTL1HDAC1HDAC3MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087669-A1 NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF TAISHO PHARMACEUTICAL CO. LTD. (JP) 2004-10-14 WO claimed