Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31682523 | 0.80 | — | — | |
| SCHEMBL24498806 | 0.76 | GRM4 (0.31) | — | |
| SCHEMBL25078994 | 0.72 | KDM4E (0.43) | PKLR | |
| SCHEMBL289062 | 0.72 | GRM4 (0.31) | — | |
| SCHEMBL23120378 | 0.72 | GRM4 (0.31) | — | |
| SCHEMBL21585781 | 0.68 | TRPV4 (0.35) | — | |
| SCHEMBL3221951 | 0.67 | ALDH1A1 (0.41) | — | |
| SCHEMBL13082703 | 0.66 | FBP1 (0.31) | — | |
| SCHEMBL2563593 | 0.64 | KDM4E (0.56) | — | |
| SCHEMBL289096 | 0.64 | GRM4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |