Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7657198 | 0.81 | TSHR (0.50) | CYP2C19ALDH1A1TSHRTDP1 | |
| Trifluoroacetic Acid SCHEMBL3591146 | 0.80 | ALDH1A1 (0.39) | CES1CYP2C19ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL27529311 | 0.77 | ALDH1A1 (0.37) | CES1CYP2C19ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL14562413 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL11789184 | 0.74 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL4147574 | 0.74 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL1262416 | 0.73 | — | — | |
| Trifluoroacetic Acid SCHEMBL3499424 | 0.73 | — | — | |
| Trifluoroacetic Acid SCHEMBL72727 | 0.73 | — | — | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.72 | ALDH1A1 (0.44) | CES1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230266321-A1 | LIVE CELL ENGAGEMENT ASSAY | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | 2023-08-24 | — | — | US | disclosed |
| EP-4087868-A1 | SMALL MOLECULE MODULATORS KSR-BOUND MEK | Icahn School of Medicine at Mount Sinai (US) | 2022-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230266321-A1 | LIVE CELL ENGAGEMENT ASSAY | KSR1, KSR2, ARAF | CES1 2476/4885CYP2C19 3425/4885ALDH1A1 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.