Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.37 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29211328 | 1.00 | DHFR (0.37) | DHFRDCPSKITCSF1RKMT2A | |
| SCHEMBL28892418 | 0.83 | KIT (0.37) | KITCSF1RKMT2AKDREPHA2 | |
| SCHEMBL30003338 | 0.83 | KIT (0.37) | KITCSF1RKMT2AKDREPHA2 | |
| SCHEMBL30003319 | 0.82 | GAA (0.40) | KMT2APKMCYP1A2MAPTMEN1 | |
| SCHEMBL28892714 | 0.82 | GAA (0.40) | KMT2APKMCYP1A2MAPTMEN1 | |
| SCHEMBL30002757 | 0.82 | KIT (0.34) | DHFRDCPSKITCSF1RKMT2A | |
| SCHEMBL28892349 | 0.82 | KIT (0.34) | DHFRDCPSKITCSF1RKMT2A | |
| SCHEMBL30002396 | 0.81 | KIT (0.35) | DHFRKITCSF1RKMT2AMAPT | |
| SCHEMBL28892739 | 0.81 | KIT (0.35) | DHFRKITCSF1RKMT2AMAPT | |
| SCHEMBL30002031 | 0.79 | DHFR (0.38) | DHFRDCPSKITCSF1RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |