Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.30 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892739 | 1.00 | KIT (0.35) | KITCSF1RSMN1; SMN2GAAMAPT | |
| SCHEMBL30002604 | 0.90 | NPC1 (0.34) | KITCSF1RSMN1; SMN2GAANPC1 | |
| SCHEMBL28892360 | 0.90 | NPC1 (0.34) | KITCSF1RSMN1; SMN2GAANPC1 | |
| SCHEMBL28892349 | 0.83 | KIT (0.34) | KITCSF1RSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL30002757 | 0.83 | KIT (0.34) | KITCSF1RSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL28892558 | 0.81 | LMNA (0.38) | SMN1; SMN2GAAMAPTALDH1A1MEN1 | |
| SCHEMBL30002409 | 0.81 | LMNA (0.38) | SMN1; SMN2GAAMAPTALDH1A1MEN1 | |
| SCHEMBL29211328 | 0.81 | DHFR (0.37) | KITCSF1RSMN1; SMN2MAPTMEN1 | |
| SCHEMBL30002519 | 0.81 | DHFR (0.37) | KITCSF1RSMN1; SMN2MAPTMEN1 | |
| SCHEMBL28892774 | 0.79 | KIT (0.35) | KITSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |