Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863826 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HPGDGAALMNA | |
| SCHEMBL2091236 | 0.86 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1GAALMNANPC1 | |
| SCHEMBL14817806 | 0.86 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1HPGDGAALMNA | |
| SCHEMBL2091233 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL4304855 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL19462360 | 0.83 | HDAC1 (0.73) | SMN1; SMN2ALDH1A1HPGDHDAC1NPC1 | |
| SCHEMBL1430696 | 0.82 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1HPGDGAALMNA | |
| SCHEMBL30368335 | 0.82 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1HPGDGAALMNA | |
| SCHEMBL30368339 | 0.82 | HDAC1 (0.49) | SMN1; SMN2ALDH1A1HPGDGAALMNA | |
| SCHEMBL11307107 | 0.82 | LMNA (0.53) | SMN1; SMN2ALDH1A1HPGDGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |