SCHEMBL6129362

SCHEMBL6129362

Cc1ccc2scnc2c1Cl

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP2A6 P11509 1/20 0.32
TRPM5 Q9NZQ8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7458773 0.79 ALDH1A1 (0.35) ALDH1A1HSD17B10MAPK1SMN1; SMN2NPSR1
SCHEMBL6129371 0.76 MAPT (0.41) ALDH1A1HSD17B10TRPM5
SCHEMBL30002773 0.76 MAPT (0.41) ALDH1A1HSD17B10TRPM5
SCHEMBL25079249 0.76 P4HB (0.39) ALDH1A1HSD17B10MAPK1SMN1; SMN2NPSR1
SCHEMBL30949588 0.76 PI4KA (0.34) ALDH1A1HSD17B10MAPK1SMN1; SMN2NPSR1
SCHEMBL22025575 0.76 ALDH1A1 (0.33) ALDH1A1HSD17B10MAPK1SMN1; SMN2NPSR1
SCHEMBL31389476 0.76 ALDH1A1 (0.33) ALDH1A1HSD17B10MAPK1SMN1; SMN2NPSR1
SCHEMBL18876087 0.76 ALDH1A1 (0.33) ALDH1A1HSD17B10MAPK1SMN1; SMN2NPSR1
SCHEMBL5160632 0.75 ALDH1A1 (0.46) ALDH1A1HSD17B10
SCHEMBL18879673 0.72 CYP1A2 (0.32) ALDH1A1HSD17B10MAPK1SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200165519-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND RETARDATION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-28 US disclosed
US-20190276744-A1 LIQUID CRYSTAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-09-12 US disclosed
US-10407619-B2 Liquid crystal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-09-10 US disclosed
US-20170335191-A1 LIQUID CRYSTAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-23 US disclosed
US-20170335191-A1 LIQUID CRYSTAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-23 US disclosed
US-20170306234-A1 LIQUID CRYSTAL COMPOSITION, METHOD OF PRODUCING THE SAME, AND RETARDATION FILM CONSTITUTED FROM THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-26 US disclosed
US-20170283700-A1 LIQUID CRYSTAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-05 US disclosed
US-20170145312-A1 LIQUID CRYSTAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-25 US disclosed
US-20170145312-A1 LIQUID CRYSTAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-25 US disclosed
EP-1089982-A4 METHODS OF INHIBITING CORROSION USING ISOMERS OF CHLORO-METHYLBENZOTRIAZOLE BETZDEARBORN INC (US) 2005-04-06 EP disclosed
EP-1089982-A1 METHODS OF INHIBITING CORROSION USING ISOMERS OF CHLORO-METHYLBENZOTRIAZOLE BetzDearborn Inc (US) 2001-04-11 EP disclosed
WO-1999067222-A1 METHODS OF INHIBITING CORROSION USING ISOMERS OF CHLORO-METHYLBENZOTRIAZOLE BETZDEARBORN INC. (US) 1999-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170335191-A1 LIQUID CRYSTAL COMPOSITION RCC1, CCDC47, ACIN1 ALDH1A1 4362/4885HSD17B10 2059/4885MAPK1 2701/4885
US-10407619-B2 Liquid crystal composition RCC1, CCDC47, ACIN1 ALDH1A1 4362/4885HSD17B10 2059/4885MAPK1 2701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.