Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL5393357 | 0.92 | HDAC1 (0.47) | ALOX15HDAC3CA12CA1IDO1 | |
| SCHEMBL7468252 | 0.80 | GFER (0.54) | CA12CA1CA9GAAKMT2A | |
| SCHEMBL554489 | 0.79 | ALOX15 (0.56) | ALOX15HDAC3CA12CA1IDO1 | |
| SCHEMBL4556754 | 0.78 | ALDH1A1 (0.55) | ALOX15CA1RAB9APTGS2KMT2A | |
| SCHEMBL7322538 | 0.77 | HDAC3 (0.54) | ALOX15HDAC3CA12CA1IDO1 | |
| SCHEMBL262369 | 0.77 | ALOX15 (0.54) | ALOX15HDAC3CA12CA1IDO1 | |
| SCHEMBL11151143 | 0.77 | ALOX15 (0.54) | ALOX15HDAC3CA12CA1IDO1 | |
| SCHEMBL3247730 | 0.77 | ALOX15 (0.54) | ALOX15HDAC3CA12CA1IDO1 | |
| SCHEMBL7467601 | 0.77 | HDAC1 (0.62) | HDAC3HDAC1HDAC2HDAC6GAA | |
| SCHEMBL17099926 | 0.76 | ALOX15 (0.52) | ALOX15HDAC3CA12CA1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868820-B2 | Polyarylene materials | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-01-16 | — | — | US | claimed |
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | claimed |
| US-20160060393-A1 | POLYARYLENE MATERIALS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2016-03-03 | — | — | US | claimed |
| EP-2990430-A1 | POLYARYLENE MATERIALS | Rohm and Haas Electronic Materials LLC (US) | 2016-03-02 | — | — | EP | claimed |
| EP-2099755-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | Glenmark Pharmaceuticals S.A. (CH) | 2009-09-16 | — | — | EP | claimed |
| EP-1313713-B1 | 4-PYRIMIDINAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS | ORTHO MCNEIL PHARM INC (US) | 2008-06-11 | — | — | EP | claimed |
| WO-2008062276-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-05-29 | — | — | WO | claimed |
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | claimed |
| EP-1060178-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER (US) | 2003-09-03 | — | — | EP | claimed |
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | claimed |
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |
| EP-0438230-B1 | Indole-substituted five-membered heteroaromatic compounds | MERCK SHARP & DOHME (GB) | 1997-04-23 | — | — | EP | claimed |
| EP-0204571-B1 | SELECTED DIFLUORO DERIVATIVES | ICI AMERICAS INC. (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0060094-B1 | GUANIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-22 | — | — | EP | claimed |
| JP-6157441-A | — | — | None | — | — | JP | disclosed |
| US-12379660-B2 | Adhesion promoting photoresist underlayer composition | DUPONT ELECTRONIC MATERIALS INTERNATIONAL, LLC (US) | 2025-08-05 | — | — | US | disclosed |
| CN-117510504-A | Protein kinase degradation agent, medicine and application | 深圳市新樾生物科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |
| US-20080227797-A1 | Pyridopyrimidine Derivatives as Pde4 Inhibitors for the Treatment of Inflammatory and Immune Diseases | ASTRAZENECA AB (SE) | 2008-09-18 | — | — | US | disclosed |
| JP-H06157441-A | PHOTOPOLYMERIZABLE DIACETYLENE COMPOUND | SEKISUI CHEM CO LTD | 1994-06-03 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227797-A1 | Pyridopyrimidine Derivatives as Pde4 Inhibitors for the Treatment of Inflammatory and Immune Diseases | PDE4A, PDE4B, PDE5A | ALOX15 1639/4885HDAC3 2589/4885CA12 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.