Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892277 | 1.00 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL28892864 | 0.87 | DHFR (0.43) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30002823 | 0.87 | DHFR (0.43) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL28892414 | 0.81 | L3MBTL1 (0.48) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL17208267 | 0.72 | HDAC6 (0.52) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30003250 | 0.70 | NSD2 (0.41) | MEN1KMT2AMAPTALDH1A1NSD2 | |
| SCHEMBL28892537 | 0.70 | NSD2 (0.41) | MEN1KMT2AMAPTALDH1A1NSD2 | |
| SCHEMBL5118383 | 0.70 | HDAC6 (0.50) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL12748203 | 0.70 | HDAC6 (0.60) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL28892141 | 0.69 | HTR2A (0.37) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |