Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892864 | 1.00 | DHFR (0.43) | DHFRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL30002838 | 0.87 | MEN1 (0.55) | DHFRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL28892277 | 0.87 | MEN1 (0.55) | DHFRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL30002459 | 0.82 | GAA (0.48) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL30002031 | 0.81 | DHFR (0.38) | DHFRMAPTKMT2AMEN1ADORA2A | |
| SCHEMBL28892688 | 0.80 | CD274 (0.35) | DHFRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL28892414 | 0.77 | L3MBTL1 (0.48) | DHFRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL28892141 | 0.69 | HTR2A (0.37) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL28892399 | 0.68 | KIT (0.39) | MAPTKMT2AMEN1GAATDP1 | |
| SCHEMBL622763 | 0.64 | NQO2 (0.55) | ALDH1A1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |