Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616980 | 1.00 | RAPGEF4 (0.38) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29360228 | 0.82 | RAPGEF4 (0.37) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9103439 | 0.82 | RAPGEF4 (0.37) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL30888383 | 0.81 | RAPGEF4 (0.36) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27225358 | 0.81 | RAPGEF4 (0.36) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL16599611 | 0.81 | RAPGEF4 (0.36) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28628697 | 0.80 | RAPGEF4 (0.35) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28658591 | 0.80 | CYP1A2 (0.40) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL31716978 | 0.79 | RAPGEF4 (0.39) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL30888439 | 0.79 | RAPGEF4 (0.34) | RAPGEF4F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214519-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-10-13 | — | — | WO | disclosed |