Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28653697 | 0.84 | MAPT (0.39) | CYP1A2CYP3A4CYP2C19MAPTMAPK1 | |
| SCHEMBL20636696 | 0.83 | MAPK1 (0.42) | CYP1A2CYP3A4CYP2C19MAPTMAPK1 | |
| SCHEMBL28650183 | 0.81 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2C19MAPTMAPK1 | |
| SCHEMBL12539750 | 0.80 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19MAPTMAPK1 | |
| SCHEMBL616980 | 0.80 | RAPGEF4 (0.38) | MAPTMAPK1MEN1KMT2ATSHR | |
| SCHEMBL30002890 | 0.80 | RAPGEF4 (0.38) | MAPTMAPK1MEN1KMT2ATSHR | |
| SCHEMBL28670348 | 0.80 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C19MAPTMAPK1 | |
| SCHEMBL28650491 | 0.79 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C19MAPTMAPK1 | |
| SCHEMBL20512225 | 0.77 | CYP1A2 (0.34) | CYP1A2CYP3A4CYP2C19MAPTMAPK1 | |
| SCHEMBL26527039 | 0.76 | KIF11 (0.41) | MAPK1KMT2ATSHRKIF11CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963851-B | Fused bicyclic pyridine compounds and their use as AMPA receptor modulators | 詹森药业有限公司 | 2021-11-30 | — | — | CN | disclosed |