Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892601 | 1.00 | MTNR1A (0.56) | MTNR1AMTNR1BMCHR1HTR2CMEN1 | |
| SCHEMBL14400281 | 0.84 | MTNR1A (0.61) | MTNR1AMTNR1BMCHR1HTR2C | |
| SCHEMBL31332052 | 0.80 | MTNR1A (0.63) | MTNR1AMTNR1BMCHR1 | |
| SCHEMBL3405870 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1BMEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL20561917 | 0.79 | MTNR1A (0.61) | MTNR1AMTNR1BMCHR1 | |
| SCHEMBL31331960 | 0.78 | MTNR1A (0.58) | MTNR1AMTNR1B | |
| SCHEMBL592558 | 0.77 | NPC1 (0.40) | MTNR1AMTNR1BMEN1NPC1LMNA | |
| SCHEMBL13738201 | 0.77 | METAP2 (0.53) | MEN1LMNARAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1222885 | 0.77 | BACE1 (0.53) | MTNR1AMTNR1BMCHR1NPC1LMNA | |
| SCHEMBL14837467 | 0.75 | MTNR1A (0.52) | MTNR1AMTNR1BHTR2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |