SCHEMBL31331960

SCHEMBL31331960

COc1ccc2cccc(CCN(C)C)c2n1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 12/20 0.58
MTNR1B P49286 12/20 0.58
HTR2A P28223 3/20 0.54
TERT O14746 1/20 0.41
NOS1 P29475 1/20 0.40
TAAR1 Q96RJ0 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27366783 1.00 MTNR1A (0.58) MTNR1AMTNR1BHTR2ATERTNOS1
SCHEMBL27366785 0.81 MTNR1A (0.63) MTNR1AMTNR1BHTR2ATAAR1
SCHEMBL31332052 0.81 MTNR1A (0.63) MTNR1AMTNR1BHTR2ATAAR1
Hydrochloric Acid SCHEMBL20561917 0.80 MTNR1A (0.61) MTNR1AMTNR1BHTR2ATAAR1
SCHEMBL14400281 0.79 MTNR1A (0.61) MTNR1AMTNR1B
SCHEMBL30003079 0.78 MTNR1A (0.56) MTNR1AMTNR1B
SCHEMBL28892601 0.78 MTNR1A (0.56) MTNR1AMTNR1B
SCHEMBL25030034 0.75 HRH1 (0.38) MTNR1AMTNR1BHTR2ANOS1
SCHEMBL3405870 0.74 MTNR1A (0.52) MTNR1AMTNR1B
SCHEMBL14895522 0.74 MTNR1A (0.60) MTNR1AMTNR1BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 MTNR1A 1247/4885MTNR1B 757/4885HTR2A 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.