Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1091823 | 1.00 | HPGD (0.50) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9075726 | 0.86 | HPGD (0.68) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL46646 | 0.84 | ALDH1A1 (0.71) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27385633 | 0.82 | HPGD (0.48) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18930988 | 0.82 | NNMT (0.55) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2654849 | 0.81 | ALDH1A1 (0.52) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19781647 | 0.79 | NPC1 (0.48) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL247044 | 0.79 | MAPK1 (0.61) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15372282 | 0.79 | CYP1A2 (0.46) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9671972 | 0.79 | ALDH1A1 (0.46) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347590-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2024-04-10 | — | — | EP | disclosed |
| CN-117715909-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-03-15 | — | — | CN | disclosed |
| WO-2022253259-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | WO | disclosed |