Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30787479 | 0.77 | MAOB (0.60) | PSMB5CA2MAOBMAOAALDH1A1 | |
| SCHEMBL30956090 | 0.77 | MAOB (0.59) | PSMB5CA2MAOBMAOAALDH1A1 | |
| SCHEMBL30956084 | 0.72 | PSMB5 (0.46) | PSMB5CA2MAOBALDH1A1MAPT | |
| SCHEMBL9634215 | 0.72 | CA2 (0.60) | PSMB5CA2MAOBMAOAKDM4C | |
| SCHEMBL28902179 | 0.72 | MAOB (0.64) | CA2MAOBMAOANPC1MAPT | |
| SCHEMBL6408649 | 0.71 | MAOB (0.50) | CA2MAOBMAOAALDH1A1NPC1 | |
| SCHEMBL30956075 | 0.71 | MAOB (0.52) | PSMB5CA2MAOBMAOAALDH1A1 | |
| SCHEMBL30956076 | 0.71 | MAOB (0.60) | CA2MAOBMAOAALDH1A1KDM4C | |
| SCHEMBL30956083 | 0.71 | MAOB (0.80) | CA2MAOBMAOAALDH1A1KDM4C | |
| SCHEMBL30003353 | 0.70 | LMNA (0.52) | PSMB5CA2MAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382302-A1 | Anticancer polyheterocyclic compounds and associated methods | UNIV OF DENVER (US) | 2025-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382302-A1 | Anticancer polyheterocyclic compounds and associated methods | HCCS, POLI, PARP1 | PSMB5 1163/4885CA2 4075/4885MAOB 2898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.