⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265716 | 0.78 | LMNA (0.32) | — | |
| SCHEMBL1923565 | 0.77 | — | — | |
| SCHEMBL25559736 | 0.75 | CYP19A1 (0.31) | — | |
| SCHEMBL996985 | 0.74 | ADRB2 (0.37) | — | |
| SCHEMBL441306 | 0.74 | ADRB2 (0.37) | — | |
| SCHEMBL996997 | 0.74 | APLNR (0.38) | — | |
| SCHEMBL22778736 | 0.74 | — | — | |
| SCHEMBL1000434 | 0.74 | ADRB2 (0.37) | — | |
| SCHEMBL9610894 | 0.73 | LMNA (0.40) | — | |
| Hydrochloric Acid SCHEMBL28480125 | 0.72 | ADRB2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287070-A1 | FUSED HETEROCYCLIC DERIVATIVES | JOHNSON & JOHNSON (CHINA) INVESTMENT LTD. (CN) | 2024-08-29 | — | — | US | disclosed |
| EP-4347590-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2024-04-10 | — | — | EP | disclosed |
| CN-117715909-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-03-15 | — | — | CN | disclosed |
| WO-2022253259-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | WO | disclosed |