Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | FABP7 | O15540 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12398445 | 1.00 | ALDH1A1 (0.51) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL10291596 | 1.00 | ALDH1A1 (0.51) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL24535022 | 1.00 | ALDH1A1 (0.51) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL17613464 | 1.00 | ALDH1A1 (0.51) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL4269208 | 0.91 | SMN1; SMN2 (0.48) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL4269550 | 0.91 | SMN1; SMN2 (0.48) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL715194 | 0.91 | SMN1; SMN2 (0.48) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL3345699 | 0.91 | SMN1; SMN2 (0.48) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL3345701 | 0.91 | SMN1; SMN2 (0.48) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL9002126 | 0.88 | ALDH1A1 (0.60) | ALDH1A1NAMPTHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332726-A1 | NITROXIDE DERIVATIVE OF ROCK KINASE INHIBITOR | VIVAVISION (SHANGHAI) LTD (CN) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332726-A1 | NITROXIDE DERIVATIVE OF ROCK KINASE INHIBITOR | ROCK1, NOS1, ROCK2 | ALDH1A1 3959/4885NAMPT 858/4885HPGD 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.