SCHEMBL30003457

SCHEMBL30003457

O=C(O)C(O)c1c[nH]nn1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
MAPK1 P28482 1/20 0.35
POLB P06746 1/20 0.31
PKM P14618 1/20 0.31
PTPN1 P18031 1/20 0.31
PTPN7 P35236 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
ESR2 Q92731 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5624764 0.82
SCHEMBL16145065 0.81 SRC (0.33)
SCHEMBL2161089 0.78 PTGS2 (0.33) LMNAPOLBBLM
Hydrochloric Acid SCHEMBL29604330 0.76 POLB (0.33) LMNAPOLBBLM
SCHEMBL28017110 0.74
SCHEMBL10761856 0.73 AKR1C3 (0.36)
SCHEMBL4139716 0.73 L3MBTL1 (0.39) POLBKMT2AL3MBTL1
SCHEMBL28863032 0.72 L3MBTL1 (0.40) LMNAMAPK1POLBPKMKMT2A
SCHEMBL2645752 0.71
SCHEMBL10924163 0.70 CYP2D6 (0.50) LMNAMAPK1POLBKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4087836-B1 PROCESSES FOR PREPARING TRIAZOLE GLYCOLATE OXIDASE INHIBITORS CANTERO THERAPEUTICS INC (US) 2025-10-08 EP disclosed
CN-114945559-B Preparation method of triazole glycollic acid oxidase inhibitor 坎特罗治疗有限公司 2025-03-11 CN disclosed
CN-114945559-B Preparation method of triazole glycollic acid oxidase inhibitor 坎特罗治疗有限公司 2025-03-11 CN disclosed
EP-4087836-A1 PROCESSES FOR PREPARING TRIAZOLE GLYCOLATE OXIDASE INHIBITORS Cantero Therapeutics, Inc. (US) 2022-11-16 EP disclosed