Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14925215 | 0.81 | LMNA (0.56) | KMT2ATSHRALDH1A1HSD17B10LMNA | |
| SCHEMBL298546 | 0.76 | MAPK1 (0.56) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL279608 | 0.73 | MEN1 (0.74) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL299338 | 0.73 | NAMPT (0.61) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL76649 | 0.71 | GAA (0.68) | TSHRALDH1A1KDM4EGAAHPGD | |
| SCHEMBL763452 | 0.71 | HTT (0.78) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL1895320 | 0.71 | CNR1 (0.61) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17788501 | 0.71 | HTT (0.71) | KMT2ATSHRALDH1A1GAALMNA | |
| SCHEMBL3980169 | 0.71 | MEN1 (0.74) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL5222020 | 0.70 | SMN1; SMN2 (0.67) | TSHRALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |