Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.69 |
| ▸ | THRB | P10828 | 14/20 | 0.69 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.69 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.65 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | ASPH | Q12797 | 1/20 | 0.56 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.56 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508977 | 1.00 | THRA (0.69) | THRATHRBEGLN1BBOX1FTO | |
| SCHEMBL1509116 | 0.96 | THRA (0.75) | THRATHRBEGLN1BBOX1FTO | |
| SCHEMBL30004356 | 0.96 | THRA (0.75) | THRATHRBEGLN1BBOX1FTO | |
| SCHEMBL4081493 | 0.89 | THRA (0.56) | THRATHRBEGLN1BBOX1FTO | |
| SCHEMBL522875 | 0.88 | THRA (0.64) | THRATHRBEGLN1BBOX1FTO | |
| SCHEMBL31028948 | 0.88 | THRA (0.64) | THRATHRBEGLN1BBOX1FTO | |
| SCHEMBL522871 | 0.87 | EGLN1 (0.49) | THRATHRBEGLN1BBOX1FTO | |
| SCHEMBL523521 | 0.86 | THRA (0.91) | THRATHRBEGLN1BBOX1FTO | |
| SCHEMBL1656320 | 0.85 | EGLN2 (0.75) | EGLN1EGLN2 | |
| SCHEMBL4075898 | 0.85 | THRA (0.55) | THRATHRBEGLN1BBOX1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298301-B2 | MEDICAMENTS FOR TREATING ANEMIA ASSOCIATED WITH KIDNEY DISEASE | FIBROGEN INC (US) | 2022-11-16 | — | — | EP | disclosed |