Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211530 | 0.84 | ALDH1A1 (0.50) | KMT2AALDH1A1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL16569907 | 0.81 | KMT2A (0.66) | KMT2AL3MBTL1ALDH1A1CYP2C9POLB | |
| SCHEMBL20683121 | 0.80 | KMT2A (0.64) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6283810 | 0.80 | KMT2A (0.64) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7683509 | 0.80 | KMT2A (0.64) | KMT2AL3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL30005500 | 0.77 | KMT2A (0.59) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30005525 | 0.77 | KMT2A (0.59) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL26120761 | 0.77 | ALDH1A1 (0.49) | KMT2AALDH1A1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL647372 | 0.76 | KMT2A (1.00) | KMT2AL3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL4851187 | 0.75 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1PTGS2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |