Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4210157 | 0.89 | KMT2A (0.46) | L3MBTL1KMT2AKEAP1NFE2L2POLB | |
| SCHEMBL4752383 | 0.86 | KMT2A (0.42) | L3MBTL1KMT2AKEAP1NFE2L2POLB | |
| Trifluoroacetic Acid SCHEMBL30005064 | 0.84 | KMT2A (0.55) | L3MBTL1KMT2APOLBTSHRALOX15 | |
| SCHEMBL5186948 | 0.77 | KMT2A (0.47) | L3MBTL1KMT2ATSHRALOX15 | |
| Trifluoroacetic Acid SCHEMBL1628483 | 0.77 | PTK2 (0.44) | PTK2POLBSMN1; SMN2 | |
| SCHEMBL4209375 | 0.74 | ALDH1A1 (0.54) | L3MBTL1POLBSMN1; SMN2PARP1RPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL27999207 | 0.73 | L3MBTL1 (0.44) | L3MBTL1KMT2APARP1PDK2KLK1 | |
| Trifluoroacetic Acid SCHEMBL1786800 | 0.73 | NPC1 (0.45) | L3MBTL1KMT2APOLBTSHR | |
| Trifluoroacetic Acid SCHEMBL5072107 | 0.73 | NPC1 (0.45) | L3MBTL1KMT2APOLBTSHR | |
| SCHEMBL28002534 | 0.71 | KMT2A (0.66) | L3MBTL1KMT2APOLBTSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |