Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4210157 | 0.93 | KMT2A (0.46) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5186948 | 0.92 | KMT2A (0.47) | KMT2AALOX15ALDH1A1KDM4EHPGD | |
| Trifluoroacetic Acid SCHEMBL30005486 | 0.86 | L3MBTL1 (0.40) | KMT2AALOX15KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL166441 | 0.81 | KMT2A (0.61) | KMT2AALOX15ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27540668 | 0.81 | ALB (0.47) | KMT2AALOX15ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL4209375 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL28002534 | 0.75 | KMT2A (0.66) | KMT2AALOX15ALDH1A1HSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30006002 | 0.73 | KMT2A (0.64) | KMT2AALOX15ALDH1A1HSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30004917 | 0.73 | KMT2A (0.64) | KMT2AALOX15ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL30005605 | 0.73 | KMT2A (0.68) | KMT2AALOX15ALDH1A1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135488-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-11-13 | — | — | WO | disclosed |