Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005500 | 0.88 | KMT2A (0.59) | KMT2AL3MBTL1POLBTSHRALDH1A1 | |
| SCHEMBL19084967 | 0.76 | CSNK2A1 (0.49) | KMT2AL3MBTL1POLBTSHRALDH1A1 | |
| SCHEMBL30005614 | 0.75 | KMT2A (0.45) | KMT2AL3MBTL1POLBTSHRCYP19A1 | |
| SCHEMBL7689156 | 0.75 | C5AR1 (0.49) | KMT2ATSHRALDH1A1USP2MAPT | |
| SCHEMBL28271886 | 0.71 | ALDH1A1 (0.45) | KMT2APOLBALDH1A1USP2MAPT | |
| SCHEMBL30005767 | 0.71 | KMT2A (0.48) | KMT2AL3MBTL1POLBALDH1A1AKR1C2 | |
| SCHEMBL222373 | 0.71 | KMT2A (0.68) | KMT2AL3MBTL1POLBTSHRALDH1A1 | |
| SCHEMBL30005605 | 0.71 | KMT2A (0.68) | KMT2AL3MBTL1POLBTSHRALDH1A1 | |
| SCHEMBL7683485 | 0.68 | ACLY (0.46) | KMT2AL3MBTL1POLBTSHRCYP19A1 | |
| SCHEMBL7558061 | 0.67 | CSNK2A1 (0.44) | KMT2AL3MBTL1POLBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |