Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TGM1 | P22735 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006561 | 0.89 | MEN1 (0.52) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30005833 | 0.83 | MAPT (0.55) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30005698 | 0.76 | MEN1 (0.48) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL30006662 | 0.76 | ALDH1A1 (0.72) | KMT2AMEN1LMNASMN1; SMN2ALOX15 | |
| SCHEMBL30004774 | 0.75 | ALDH1A1 (0.58) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL30006454 | 0.71 | ALDH1A1 (0.67) | KMT2AMEN1SMN1; SMN2ALOX15ALDH1A1 | |
| SCHEMBL30005757 | 0.69 | MEN1 (0.51) | KMT2AMEN1LMNASMN1; SMN2ALOX15 | |
| SCHEMBL30006458 | 0.69 | ALDH1A1 (0.73) | KMT2AMEN1SMN1; SMN2ALOX15HTT | |
| SCHEMBL30005455 | 0.69 | TDP1 (0.52) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL30004926 | 0.69 | ALDH1A1 (0.69) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |