Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.48 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.48 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.48 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006561 | 0.89 | MEN1 (0.52) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30005698 | 0.85 | MEN1 (0.48) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30004774 | 0.84 | ALDH1A1 (0.58) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30005508 | 0.83 | KMT2A (0.49) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30005757 | 0.79 | MEN1 (0.51) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30005455 | 0.78 | TDP1 (0.52) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL30005703 | 0.77 | MAPT (0.47) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL30005561 | 0.76 | TDP1 (0.49) | MAPTPOLBMEN1KMT2ATP53 | |
| SCHEMBL30005953 | 0.76 | TDP1 (0.49) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL175270 | 0.75 | NAMPT (0.81) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |