Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006561 | 0.86 | MEN1 (0.52) | MEN1KMT2AATMSMN1; SMN2NAMPT | |
| SCHEMBL30005833 | 0.85 | MAPT (0.55) | MEN1KMT2AATMSMN1; SMN2MAPT | |
| SCHEMBL30004774 | 0.83 | ALDH1A1 (0.58) | MEN1KMT2AATMSMN1; SMN2MAPT | |
| SCHEMBL30005757 | 0.76 | MEN1 (0.51) | MEN1KMT2AATMSMN1; SMN2MAPT | |
| SCHEMBL30005508 | 0.76 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2NAMPTMAPT | |
| SCHEMBL30005455 | 0.75 | TDP1 (0.52) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL175270 | 0.74 | NAMPT (0.81) | NAMPTCYP2C9 | |
| SCHEMBL30005703 | 0.74 | MAPT (0.47) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL30005465 | 0.73 | ALDH1A1 (0.73) | MEN1KMT2AATMSMN1; SMN2MAPT | |
| SCHEMBL30005561 | 0.73 | TDP1 (0.49) | MEN1KMT2AATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |