Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 11/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006040 | 0.93 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1NPSR1KIF18A | |
| SCHEMBL30004834 | 0.91 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1NPSR1PKM | |
| Hydrochloric Acid SCHEMBL30006638 | 0.90 | NAMPT (0.35) | ALDH1A1KMT2AMEN1NPSR1KIF18A | |
| Hydrochloric Acid SCHEMBL30005741 | 0.88 | ALDH1A1 (0.34) | ALDH1A1KMT2AMEN1NPSR1KIF18A | |
| SCHEMBL30006778 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1NPSR1KIF18A | |
| SCHEMBL30005790 | 0.85 | NAMPT (0.42) | ALDH1A1KMT2AMEN1NPSR1KIF18A | |
| SCHEMBL30005005 | 0.85 | NAMPT (0.36) | ALDH1A1KMT2AMEN1NPSR1KIF18A | |
| Hydrochloric Acid SCHEMBL30004650 | 0.85 | EP300 (0.33) | ALDH1A1KIF18ARXFP1 | |
| SCHEMBL30005065 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1NPSR1PKM | |
| Hydrochloric Acid SCHEMBL30005778 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1NPSR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |