Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006040 | 0.90 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1NPSR1POLB | |
| SCHEMBL30005710 | 0.89 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1NPSR1POLB | |
| SCHEMBL31518590 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1NPSR1POLB | |
| SCHEMBL30005517 | 0.87 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1NPSR1KIF18A | |
| Hydrochloric Acid SCHEMBL30006638 | 0.85 | NAMPT (0.35) | ALDH1A1KMT2AMEN1NPSR1POLB | |
| Hydrochloric Acid SCHEMBL30005741 | 0.85 | ALDH1A1 (0.34) | ALDH1A1KMT2AMEN1NPSR1KIF18A | |
| SCHEMBL30005790 | 0.84 | NAMPT (0.42) | ALDH1A1KMT2AMEN1NPSR1KIF18A | |
| SCHEMBL31518437 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1NPSR1POLB | |
| SCHEMBL30005712 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1NPSR1POLB | |
| SCHEMBL31539274 | 0.81 | C5AR1 (0.47) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |