Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 7/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005481 | 1.00 | SMARCA2 (0.49) | SMARCA2SMARCA4PBRM1ADAMTS5MMP2 | |
| SCHEMBL22201058 | 0.89 | ADAMTS5 (0.50) | SMARCA2SMARCA4PBRM1ADAMTS5GPR119 | |
| SCHEMBL652990 | 0.88 | MEN1 (0.53) | SMARCA2SMARCA4PBRM1ADAMTS5MMP2 | |
| SCHEMBL656085 | 0.88 | MEN1 (0.53) | SMARCA2SMARCA4PBRM1ADAMTS5MMP2 | |
| SCHEMBL652991 | 0.88 | MEN1 (0.53) | SMARCA2SMARCA4PBRM1ADAMTS5MMP2 | |
| SCHEMBL23784974 | 0.88 | MAPT (0.51) | SMARCA2SMARCA4PBRM1ADAMTS5MMP2 | |
| SCHEMBL21326453 | 0.88 | MAPT (0.51) | SMARCA2SMARCA4PBRM1ADAMTS5MMP2 | |
| SCHEMBL23784876 | 0.88 | MAPT (0.51) | SMARCA2SMARCA4PBRM1ADAMTS5MMP2 | |
| SCHEMBL27985660 | 0.87 | LMNA (0.49) | SMARCA2SMARCA4PBRM1GPR119MAPT | |
| SCHEMBL17871456 | 0.86 | GPR119 (0.48) | SMARCA2SMARCA4PBRM1ADAMTS5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |