Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 10/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554888 | 0.84 | PIM1 (0.43) | KMT2AAKR1C2SMN1; SMN2MAPK1LMNA | |
| SCHEMBL6644474 | 0.82 | SMN1; SMN2 (0.53) | KMT2AAKR1C3AKR1C2SMN1; SMN2KDM4E | |
| SCHEMBL6646574 | 0.81 | KMT2A (0.43) | KMT2AKDM4EPOLBL3MBTL1CA12 | |
| SCHEMBL7558061 | 0.81 | CSNK2A1 (0.44) | KMT2AALDH1A1POLBGAAL3MBTL1 | |
| SCHEMBL7684663 | 0.79 | LMNA (0.53) | KMT2AAKR1C3AKR1C2SMN1; SMN2POLB | |
| SCHEMBL7557135 | 0.79 | KDM4E (0.42) | KMT2AAKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL7682908 | 0.79 | KEAP1 (0.42) | KMT2AKDM4EPOLBHPGDL3MBTL1 | |
| SCHEMBL7556650 | 0.79 | TSHR (0.49) | KMT2ASMN1; SMN2KDM4EALDH1A1CA1 | |
| SCHEMBL7558164 | 0.79 | KMT2A (0.42) | KMT2AALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL24497695 | 0.79 | CYP2C9 (0.50) | KMT2ASMN1; SMN2KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |