Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867134 | 0.83 | KMT2A (0.64) | LMNAKMT2APOLBL3MBTL1TSHR | |
| SCHEMBL7558061 | 0.82 | CSNK2A1 (0.44) | KMT2APOLBL3MBTL1TSHR | |
| SCHEMBL6646574 | 0.82 | KMT2A (0.43) | KMT2APOLBL3MBTL1TSHR | |
| SCHEMBL7557135 | 0.81 | KDM4E (0.42) | KMT2AAKR1C3AKR1C2POLBL3MBTL1 | |
| SCHEMBL7682908 | 0.81 | KEAP1 (0.42) | LMNAKMT2APOLBL3MBTL1TSHR | |
| SCHEMBL7558164 | 0.81 | KMT2A (0.42) | LMNAKMT2APOLBL3MBTL1TSHR | |
| SCHEMBL7556650 | 0.81 | TSHR (0.49) | LMNAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL7558215 | 0.80 | LMNA (0.49) | LMNAKMT2AAKR1C3AKR1C2TSHR | |
| SCHEMBL30005767 | 0.79 | KMT2A (0.48) | LMNAKMT2ATDP1AKR1C3AKR1C2 | |
| SCHEMBL8634139 | 0.79 | KMT2A (0.41) | LMNAKMT2APOLBL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045551-A1 | 4-benzoyl isoxazoles derivatives and their use as herbicides | MUSIL TIBOR (GB) | 2002-04-18 | — | — | US | disclosed |
| US-6323155-B1 | EXCELLENT LEVEL OF HERBICIDAL ACTIVITY TOGETHER WITH CROP TOLERANCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-11-27 | — | — | US | disclosed |
| EP-0674629-B1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE (GB) | 1998-07-08 | — | — | EP | disclosed |
| EP-0674629-A1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014782-A1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045551-A1 | 4-benzoyl isoxazoles derivatives and their use as herbicides | CBR3, CBR1, GLRA3 | LMNA 2378/4885KMT2A 3499/4885TDP1 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.