Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005697 | 0.83 | LMNA (0.56) | GAALMNAMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL30005557 | 0.82 | ALDH1A1 (0.58) | GAALMNAMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL31252083 | 0.78 | TRPV4 (0.58) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL30005725 | 0.78 | KMT2A (0.48) | GAALMNAMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL15076668 | 0.76 | SMN1; SMN2 (0.80) | GAALMNAMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL30005757 | 0.75 | MEN1 (0.51) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL30005455 | 0.74 | TDP1 (0.52) | TDP1ALDH1A1KMT2AMAPTTHRB | |
| SCHEMBL30005465 | 0.74 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL7076804 | 0.73 | LMNA (0.74) | GAALMNATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17479082 | 0.73 | LMNA (0.70) | GAALMNASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |