Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3855094 | 1.00 | LMNA (0.51) | LMNAMEN1KMT2AMAPTUSP2 | |
| SCHEMBL1883657 | 0.86 | KMT2A (0.55) | LMNAMEN1KMT2AMAPTUSP2 | |
| SCHEMBL8303311 | 0.83 | KMT2A (0.46) | LMNAKMT2AALDH1A1HTTMAPK1 | |
| SCHEMBL5435147 | 0.82 | POLB (0.55) | LMNAMEN1KMT2AMAPTUSP2 | |
| SCHEMBL6417389 | 0.82 | LMNA (0.62) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL475723 | 0.82 | LCK (0.45) | LMNAMEN1KMT2AMAPTUSP2 | |
| SCHEMBL5720785 | 0.81 | ALDH1A1 (0.47) | LMNAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL31047143 | 0.80 | BRD4 (0.47) | LMNAMEN1KMT2AMAPTUSP2 | |
| SCHEMBL222176 | 0.80 | KMT2A (0.58) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29625195 | 0.80 | KMT2A (0.58) | LMNAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |