SCHEMBL30006537

SCHEMBL30006537

CN(c1ccccc1C(=O)Cl)S(C)(=O)=O

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.66
TSHR P16473 4/20 0.56
L3MBTL1 Q9Y468 4/20 0.54
NPSR1 Q6W5P4 2/20 0.54
ALDH1A1 P00352 2/20 0.52
POLB P06746 1/20 0.52
MEN1 O00255 2/20 0.50
HSD17B10 Q99714 1/20 0.50
USP2 O75604 1/20 0.49
MAPT P10636 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30005605 0.84 KMT2A (0.68) KMT2ATSHRL3MBTL1NPSR1ALDH1A1
SCHEMBL9624386 0.84 KMT2A (0.68) KMT2ATSHRL3MBTL1NPSR1ALDH1A1
SCHEMBL222373 0.84 KMT2A (0.68) KMT2ATSHRL3MBTL1NPSR1ALDH1A1
SCHEMBL13801044 0.82 KMT2A (0.66) KMT2ATSHRL3MBTL1NPSR1ALDH1A1
SCHEMBL28002534 0.82 KMT2A (0.66) KMT2ATSHRL3MBTL1NPSR1ALDH1A1
SCHEMBL27468103 0.81 KMT2A (0.74) KMT2ATSHRL3MBTL1NPSR1ALDH1A1
Hydrochloric Acid SCHEMBL30006002 0.81 KMT2A (0.64) KMT2ATSHRL3MBTL1NPSR1ALDH1A1
Hydrochloric Acid SCHEMBL30004917 0.81 KMT2A (0.64) KMT2ATSHRL3MBTL1NPSR1ALDH1A1
SCHEMBL647372 0.79 KMT2A (1.00) KMT2ATSHRL3MBTL1NPSR1ALDH1A1
SCHEMBL456580 0.79 ALDH1A1 (0.69) KMT2ATSHRL3MBTL1NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085848-A1 ANTIBACTERIAL COMPOUNDS ARREPATH, INC. (US) 2025-04-24 WO disclosed
WO-2025054132-A1 ANTIBACTERIAL COMPOUNDS ARREPATH, INC. (US) 2025-03-13 WO disclosed
WO-2022220725-A1 LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS ZAMARATSKI EDOUARD (SE) 2022-10-20 WO disclosed