Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | ECE1 | P42892 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 2/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | KDM4B | O94953 | 1/20 | 0.49 |
| ▸ | KDM5C | P41229 | 1/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19902999 | 1.00 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2ECE1KDM4E | |
| SCHEMBL27886900 | 0.83 | ECE1 (0.51) | RAB9ANPC1SMN1; SMN2ECE1KDM4E | |
| SCHEMBL1339930 | 0.82 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2KDM4EKDM4A | |
| SCHEMBL26643227 | 0.81 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2ECE1KDM4E | |
| SCHEMBL31597120 | 0.81 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2KDM4ESTAT1 | |
| SCHEMBL2800244 | 0.79 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2KDM4ESTAT1 | |
| SCHEMBL22383456 | 0.79 | ALDH1A1 (0.61) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL23742612 | 0.78 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL13475977 | 0.76 | GRM5 (0.54) | RAB9ASMN1; SMN2ECE1KDM4EPOLB | |
| SCHEMBL1093303 | 0.76 | SMN1; SMN2 (0.60) | RAB9ANPC1SMN1; SMN2ECE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |