Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535618 | 1.00 | TGFBR1 (0.42) | TGFBR1ADORA2AADORA1ADORA2BMAP4K4 | |
| SCHEMBL30006563 | 0.80 | TGFBR1 (0.50) | TGFBR1MAP4K4 | |
| SCHEMBL23535570 | 0.80 | TGFBR1 (0.50) | TGFBR1MAP4K4 | |
| SCHEMBL23535581 | 0.76 | MAP4K4 (0.48) | TGFBR1ADORA2AADORA1MAP4K4 | |
| SCHEMBL30006714 | 0.76 | MAP4K4 (0.48) | TGFBR1ADORA2AADORA1MAP4K4 | |
| SCHEMBL29907557 | 0.76 | TGFBR1 (0.46) | TGFBR1ADORA2AADORA1ADORA2BGRM2 | |
| SCHEMBL23535625 | 0.74 | LDHA (0.45) | MAP4K4LDHA | |
| SCHEMBL30007488 | 0.74 | LDHA (0.45) | MAP4K4LDHA | |
| SCHEMBL22579271 | 0.74 | ADORA2A (0.45) | TGFBR1ADORA2AADORA1ADORA2B | |
| SCHEMBL30880733 | 0.74 | ADORA2A (0.45) | TGFBR1ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| CN-115087657-B | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-01-21 | — | — | CN | disclosed |