Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.41 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | FYN | P06241 | 6/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535581 | 1.00 | MAP4K4 (0.48) | MAP4K4TGFBR1TGFBR2PIK3CAFYN | |
| SCHEMBL23535607 | 0.83 | FYN (0.55) | FYNNPC1RAB9ADYRK3CCNT1 | |
| SCHEMBL30006113 | 0.83 | FYN (0.55) | FYNNPC1RAB9ADYRK3CCNT1 | |
| SCHEMBL17754850 | 0.78 | ALDH1A1 (0.46) | TGFBR1TGFBR2FYNKDM4ENPC1 | |
| SCHEMBL23535591 | 0.78 | FYN (0.57) | FYN | |
| SCHEMBL23535618 | 0.76 | TGFBR1 (0.42) | MAP4K4TGFBR1ADORA2AADORA1 | |
| SCHEMBL30006850 | 0.76 | TGFBR1 (0.42) | MAP4K4TGFBR1ADORA2AADORA1 | |
| SCHEMBL23551178 | 0.71 | KDM4E (0.45) | FYNKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL3323066 | 0.70 | FYN (0.65) | FYNDYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL23535614 | 0.70 | FYN (0.65) | PIK3CAFYNDYRK3CCNT1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| CN-115087657-B | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-01-21 | — | — | CN | disclosed |