Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365489 | 1.00 | MAOA (0.33) | MAOAMAOBLOXKDM4EADRA2A | |
| SCHEMBL28937922 | 0.89 | ALDH1A1 (0.36) | MAOAMAOBKDM4EHSD17B1ALDH1A1 | |
| SCHEMBL4291926 | 0.89 | PARP1 (0.33) | MAOAMAOBKDM4EALDH1A1PARP1 | |
| SCHEMBL30083746 | 0.89 | ALDH1A1 (0.36) | MAOAMAOBKDM4EHSD17B1ALDH1A1 | |
| SCHEMBL1225571 | 0.79 | MAOA (0.50) | MAOAMAOBLOXKDM4EHSD17B1 | |
| SCHEMBL30070543 | 0.79 | MAOA (0.50) | MAOAMAOBLOXKDM4EHSD17B1 | |
| Methane SCHEMBL6936064 | 0.78 | MAOA (0.49) | MAOAMAOBLOXKDM4EHSD17B1 | |
| SCHEMBL15287047 | 0.76 | MEN1 (0.41) | KDM4EPARP10PARP11PARP1 | |
| SCHEMBL8366049 | 0.76 | KDM4E (0.33) | MAOAMAOBLOXKDM4EHSD17B1 | |
| SCHEMBL29673147 | 0.76 | NOTUM (0.48) | MAOAMAOBLOXKDM4EHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684628-B | Substituted indanyl imidazole compound, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2025-06-17 | — | — | CN | disclosed |
| WO-2025038395-A1 | BENZOPYRIDINONES AND BENZOPYRIMIDINONES AS PI3K INHIBITORS | ONKURE, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| CN-118684628-A | Substituted indanyl imidazole compound, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-09-24 | — | — | CN | disclosed |
| CN-115611877-A | Sulfonamide compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-01-17 | — | — | CN | disclosed |
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |